AdministratorJune 8, 2021 at 7:02 pm463 Replies36551 XPForum Rank: Forum RegularReputation: Level 5
Let’s, first of all, try to break down the question. “Monoclonal antibody” – an antibody that is made in a lab and matches a specific antigen (or, more specific -> an epitope on the antigen).
Variable regions: the regions that attach to the epitope
Constant regions: a constant part of the antibody, it does not attach to the antigen. It’s only a part of the antibody’s structure.
“The separated variable and constant regions were then added to cells (inside the cells) infected with the virus”. So the viruses are inside the cells.
1. The constant regions can’t bind to antigens. Only variable regions do.
2. The viruses are inside the cell. For phagocytes to engulf the pathogens, they have to be extracellular.
3. Monoclonals antibodies are made in a lab for a specific epitope, unlike regular antibodies that can fit different epitopes of an antigen.
I hope it helps.
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